8 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... Bullae/Blisters • Ulceration ... • EGPA • Henoch-Schönlein ... #rash #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus Nephritis ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #differential #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Diagnosis Algorithm ... RMSF - Henoch Schonlein ... Rash: - Purpura ... #Algorithm #Causes
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Scleroderma • Henoch-Schonlein ... Purpura • Polymyalgia ... polyangiitis (MPA ... Rheumatic Fever Acute ... #Causes
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... , palpable purpura ... maculopapular rash ... vesicular rash, ... Nephrocalcinosis causes
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... , mucositis • Rash ... present) Henoch Schonlein ... tract, and often causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
• Microscopic Polyangiitis ... present • Henoch Schonlein ... tract, and often causes ... mucositis - Rash ... • ANCA (Dx: GPA
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Clinical triad of Palpable ... associated vasculitis - GPA ... polyangiitis ... vasculitis (Henoch-Schönlein