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diagnosis hematology management leukemia cll differential lymphocytic pulmonary workup abscess bronchiectasis classification common cvid disease hemeonc hodgkins igg4 immunodeficiency immunology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... lung disease ... Chest CT: • Ground-glass ... DDX - Other causes ... Malignancies • Chronic
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... head and neck, pancreas ... biliary, renal, lung ... concentration PET-CT ... • Polyclonal hypergammaglobulinemia
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Most common cause ... pneumonia • Chronic ... seen • Chest CT ... hemorrhage • Treatment ... #differential #causes
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Infection due to hypogammaglobulinemia ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... cells can indicate disease ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Most Common Causes ... in the adjacent lung ... of the affected lung ... high-resolution chest CT ... mycobacteria Treatment
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> AML: Blast crises ... Agranulocytosis • Hypogammaglobulinemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Pulmonary Nodule Evaluation is guided by nodule size & assessment of probability of malignancy. In addition is
masses & should ... The treatment of ... comorbidities, such as chronic ... obstructive pulmonary disease ... coronary artery disease
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Mediastinal mass) • CT ... number of sites of disease ... physical exam, CT ... Hodgkin Lymphoma Treatment ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #oncology
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