8 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... biliary, renal, lung ... concentration PET-CT ... increased IgG4+ cells ... #diagnosis #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
macrophages and T cells ... • Silicosis • Chronic ... Langerhans giant cells ... malignancy, and chronic ... TB #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
macrophages and T cells ... • Silicosis • Chronic ... Langerhans giant cells ... malignancy, and chronic ... TB #Diagnosis #Management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... Autoimmunity • Chronic ... lung disease ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management ... pneumonia • Chronic ... CT Lung Abscess ... Management: • ... Clindamycin in case of PCN
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacterium tuberculosis ... lung disease ... Advanced HIV (CD4 cell ... Hematologic malignancy ... Imaging, high res CT
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Squamous-Cell Carcinoma ... A chest radiograph ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT #
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Hematopoietic stem cell ... change in the lungs ... becomes a yeast cell ... nails, bronchi, lungs ... Fungal #Diagnosis #Management