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management differential hematology causes ct disease pulmonary radiology dermatology lung nejm oncology treatment abscess agglutinin anemia antinxp2 antinxp2dm arteritis babesia
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... • Chronic lung ... Chest CT: • Ground-glass ... community-acquired infections: Pneumonia
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... Clinical history ... concentration PET-CT ... increased IgG4+ cells ... workup #treatment #rheumatology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... infection • Most common ... Lung Abscess - Clinical ... ) • CXR upright ... seen • Chest CT
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Overview: • Most common ... immunophenotype Clinical ... routine CBC (rnost common ... chemotherapy for low-risk disease ... #hemeonc #diagnosis
Bronchiectasis - Permanent dilation of an airway WHAT CAN YOU SEE ON CT? 1) Lack of tapering of
CAN YOU SEE ON CT ... ) WHAT ARE COMMON ... Obstruction 6) Rheumatologic ... /Autoimmune diseae ... Bronchiectasis #pulmonary #diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Pain in Sickle Cell ... Generally affects long ... • Most common ... #differential #diagnosis ... #causes #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ducts Clinical ... Lymphocytic interstitial pneumonia ... Usual interstitial pneumonia ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... Viral Infection Clinical ... symptoms - most common ... (older) • Autoimmune ... hemolytic #anemia #hematology
Miliary Pattern - Chest Radiology • Miliary opacities are scattered, small (1 -4 mm) nodules •
throughout the lungs ... hematogenous spread of a disease ... rarely typical pneumonia ... #pulmonary #CXR ... #clinical #CT
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
or more commonly ... Rarely dominate the clinical ... syndrome • Giant cell ... Streptococcal pneumonia ... #rheumatology
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