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diagnosis differential management pulmonary infectiousdiseases activetb aids hiv latenttb lung tuberculosis abscess brain bronchiectasis classification cns crypto cryptococcal hematology hemophagocytic
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
failure, COPD, Lung ... : Imaging (CXR ... +/- High res CT ... Fungal, AFB), TB ... Diseases Fellows
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
characteristic features Clinical ... and Culture • CXR ... Tuberculosis Treatment ... Initiating Treatment ... • Check CXR and
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
characteristic features Clinical ... and Culture • CXR ... Tuberculosis Treatment ... Initiating Treatment ... • Check CXR and
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... Lung Abscess - Clinical ... seen • Chest CT ... westermani • Other: TB
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... accumulation of clinical ... Drugs, Unknown cause ... Treatment: • ... inhibitors under evaluation
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
should be based on clinical ... Antimicrobial treatment ... enhancement on CT ... Demyelinating disease ... caused by the JC
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
: TB, NTM, PNA ... in the adjacent lung ... of the affected lung ... high-resolution chest CT ... mycobacteria Treatment
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Kansasii: • Mimics TB ... Advanced HIV (CD4 ... Disease: • Clinical ... Imaging, high res CT
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Diagnosis Framework Disease ... • CT: Halo sign ... factor • May cause ... infiltrates, mimicking TB
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
worsening of that disease ... noncompliance • Clinical ... initiation Clinical ... pericarditis, peritoneal disease ... unintentional weight loss, nausea
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