7 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... biliary, renal, lung ... concentration PET-CT ... #diagnosis #management ... workup #treatment #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... lymphocytic interstitial lung ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based tests:
 • FIT: 79% sensitivity, 94% specificity for CRC
mortality 26% • CT ... lesions or SSLs • Colon ... Colorectal #Cancer #colon ... Screening #Tests #comparison ... #table #management
ACA Colorectal Cancer Screening Guidelines

When to Screen?
When to Stop?
Family History

Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based
mortality 26% • CT ... lesions or SSLs • Colon ... Colorectal #Cancer #colon ... Indications #Tests #comparison ... #table #management
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
verrucous) • Lung ... , Pancreas, Gastric ... Criteria • ↑ ESR, CRP ... Regurgitation • Colon ... Endocarditis #diagnosis #management
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
, pancreas, stomach ... , colon, and lymphoma ... , pancreas, stomach ... , colon, and lymphoma ... Myositis #Myopathy #rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
had more severe disease ... renal carcinoma • Colon ... Non-small-cell lung ... Dermatomyositis #diagnosis #management ... #rheumatology #