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diagnosis rheumatology differential blood dermatomyositis disease product reactions syndrome activation algorithm antimda5 antimda5dm antinxp2 antinxp2dm autoimmune bone classification common cvid
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... • Kikuchi Disease ... , Mediastinum, Lungs ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... head and neck, pancreas ... biliary, renal, lung ... concentration PET-CT ... #diagnosis #management
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Generally affects long ... Osteomyelitis / Septic Arthritis ... #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... lymphocytic interstitial lung ... Chest CT: • Ground-glass ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... rash) • Heart, lung ... juvenile idiopathic arthritis ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
severity of the disease ... anti-NXP2 Abs Lung ... • Arthralgia/arthritis ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
in literature (NEJM ... identifies 85 to 95% of cases ... (Cornelia NEJM ... day, followed by long ... Symptoms #Diagnosis #Management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Arthralgia and Arthritis ... MALT Lymphoma • Lung ... #Diagnosis #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Mediastinal mass) • CT ... number of sites of disease ... physical exam, CT ... classification #hematology ... #oncology #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... Related Acute Lung ... TRALI): Leading cause ... Transfusion #diagnosis #management ... #hematology #reactions
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