16 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... concentration PET-CT ... IgG4 #Related #Disease ... #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • ... Gastrointestinal inflammatory disease ... Granulomatous disease ... • Liver diseases ... disease (GLILD)
Disseminated Actinomycosis- ...Computed tomography of the chest and abdomen revealed multiple pulmonary nodules (Panel A) associated
Disseminated Actinomycosis ... effusions in both lungs ... Biopsy of the lung ... #NEJM #clinical ... #radiology #CT #
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Periodontal disease ... dentition/gingival disease ... Lung Abscess - Clinical ... loss • Late disease ... Gingival crevice disease
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... Syndrome: • Common Clinical ... thromboembolic disease ... myeloid cells NEJM ... Autoinflammatory #Somatic #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... Adult-onset Still disease ... erythematosus • Kawasaki disease ... rash) • Heart, lung ... of underlying disease
Echinococcal Cysts in the Liver- The physical examination revealed hepatomegaly with a palpable hepatic mass. Laboratory
Hydatid disease ... #clinical #NEJM ... hepatic #radiology #CT
Pulmonary Nodule
Evaluation is guided by nodule size & assessment of probability of malignancy. In addition is
a repeat chest CT ... malignancy, clinical ... obstructive pulmonary disease ... coronary artery disease ... Management options
Gastric Gyri - Pediatric Ménétrier’s Disease - Computed tomography with contrast material (Panel A shows the
Pediatric Ménétrier’s Disease ... #Clinical #Peds ... GI #Radiology #CT ... RugalHypertrophy #NEJM
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... in literature (NEJM ... cases (Cornelia NEJM ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management