14 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... concentration PET-CT ... 40% supporting long-term ... IgG4 #Related #Disease
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
calcification of both adrenal ... deficiency, or Wolman’s disease ... #clincial #peds ... #infant #NEJM # ... Wolmans #radiology #xray
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Renal Cell Carcinoma ... Summary Clinical ... locally advanced disease ... of metastatic disease ... of metastatic disease
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • ... Gastrointestinal inflammatory disease ... Granulomatous disease ... • Liver diseases ... disease (GLILD)
Extramammary Paget’s Disease - The physical examination revealed an erythematous velvety plaque with superficial white scale
Extramammary Paget’s Disease ... large atypical cells ... (Panel B) #Clinical ... #Derm #Honc #Extramammary ... ExtramammaryPaget #NEJM
Echinococcal Cysts in the Liver- The physical examination revealed hepatomegaly with a palpable hepatic mass. Laboratory
a normal white-cell ... Hydatid disease ... #clinical #NEJM ... hepatic #radiology #CT
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... associated with other diseases ... demyelinating disease ... peripheral Thyroid Disease ... Tracheobronchial disease
Clinical Manifestations of Sickle Cell Disease

Anaemia
Infection
Painful crises
Priapism
Splenomegaly
Long Term Problems - Short stature and delayed puberty, Stroke
Clinical Manifestations ... of Sickle Cell ... Disease Anaemia ... Term Problems - ... #SickleCell #Disease
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Squamous-Cell Carcinoma ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT # ... squamous #cell #
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Mediastinal mass) • CT ... number of sites of disease ... physical exam, CT ... hematology #oncology #management