15 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... concentration PET-CT ... increased IgG4+ cells ... 40% supporting long-term
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
confirmed the diagnosis ... deficiency, or Wolman’s disease ... #clincial #peds ... #infant #NEJM # ... Wolmans #radiology #xray
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Renal Cell Carcinoma ... (RCC) - Diagnosis ... Management Summary Clinical ... Imaging and Treatment ... test: abdominal CT
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (GCA) Giant cell ... Diagnosis = clinical ... in literature (NEJM ... cases (Cornelia NEJM
Esophageal Atresia and Tracheoesophageal Fistula- An infant had an apneic episode at birth and received positive-pressure
fistula, type C, was diagnosed ... cardiovascular, renal ... and developing well ... #NEJM #clinical ... type #C #chest #Xray
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Squamous-Cell Carcinoma ... biopsy confirmed a diagnosis ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT #
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Diagnosis ... RTA, TYPE I RTA Diagnosis ... ducts Clinical ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Mediastinal mass) • CT ... number of sites of disease ... physical exam, CT ... Hodgkin Lymphoma Treatment
Clinical Manifestations of Sickle Cell Disease

Anaemia
Infection
Painful crises
Priapism
Splenomegaly
Long Term Problems - Short stature and delayed puberty, Stroke
Clinical Manifestations ... of Sickle Cell ... Splenomegaly Long ... Term Problems - ... Signs #Symptoms #Diagnosis
Pyoderma Gangrenosum in Ulcerative Colitis- ...left chest (Panel A) and leg (Panel B). The physical examination
mixed inflammatory-cell ... A diagnosis of pyoderma ... #clinical #photo ... #NEJM #pyoderma ... ulcerative #colitis #derm