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diagnosis algorithm management gitelman heat heatstroke hypotonic illness low metabolic nongap pathophysiology physiologic rhabdomyolysis stroke syndrome table treatment
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Hypokalemia ... Hyperkalemia ... Drug-induced hyperkalemia ... #Acidosis #differential ... #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm Hypovolemia, UNa > 20: • Renal losses, Diuretic excess,
Causes of Hyponatremia ... - Differential ... with renal tubal acidosis ... fluids, Burns, Pancreatitis ... #nephrology
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia - Differential ... : • Hypovolemia ... Sweating, Burns, Pancreatitis ... polydipsia • Hypervolemia ... #nephrology #sodium
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... Present (Uosm ≥100): Hypovolemia ... , Hypervolemia with ... #differential # ... #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... Renal tubular acidosis ... pathophysiology #Hypokalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
exertion/training - Seizures ... • LDH ↑ • Hyperkalemia ... Hyperuricemia • Hyponatremia ... Dialysis for severe hyperkalemia ... #treatment #nephrology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Dehydration - Loss of sodium ... heat illness → Hypernatremia ... consciousness, Coma/seizure ... - Hyperkalemia ... #diagnosis #causes
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