14 results
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Secondary Causes ... #HES #eosinophilia ... #diagnosis #hematology ... #differential # ... management #eosinophils
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... causes of eosinophilia ... glucocorticoid treatment ... symptoms (eg, skin ... #diagnosis #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... Differential Diagnosis ... Myelodisplastic syndrome ... #primary #secondary ... #dermatology #Differential
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Reaction with Eosinophilia ... lymphadenopathy, eosinophilia ... Eosinophilia 4 ... : symptomatic treatment ... #dermatology #diagnosis
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Skin Lesion - Differential ... Myelodisplastic syndrome ... #secondary #systemic ... #generalized #dermatology ... #causes
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
Diagnosis Eosinophilic ... facei peripheral eosinophilia ... plasma cells, and eosinophils ... the mainstay of treatment ... #table #dermatology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential ... Diagnosis Framework ... Eosinophilic folliculitis ... Secondary syphilis ... #Diagnosis #Dermatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
• Painful or pruritic ... thrombophlebitis, pulmonary ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia ... tract, and often causes ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Diagnosis Framework ... • EGPA: - Eosinophilia ... tract, and often causes ... #diagnosis #rheumatology