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hematology management differential disease behcet capillary cell chronic cll fungal gammopathy infections leak leukemia lymphocytic mgus mycoses paraproteinemias plasmacytoma significance
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... - Differential Diagnosis ... Neurologic-Centered ... (Clarkson's) ... #hematology #oncology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Relapsing-remitting course +++ Clinical ... Monoclonal gammopathy ... filling +++ (risk of pulmonary ... #diagnosis #management ... #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... hemangiomata, clubbing Clarkson ... et diutinum Neurologic ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • MPGN: Paraneoplastic ... microglobulin Treatment ... #workup #oncology ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... (Clinical Dx). ... Arthritis, AS Treatment ... refractory disease : monoclonal ... signs #symptoms #rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... has five major clinical ... fungal stain of clinical ... : • Serology for ... ) #Mycoses #InfectiousDiseases
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... tissue composed of monoclonal ... Bone marrow Treatment ... #Plasmacytoma #Oncology ... #Diagnosis #Workup
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