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diagnosis dermatology differential cryofibrinogenemia cryoglobulinemic cutaneous erythematosus gpa granulomatosis hematology lupus management polyangiitis rash sjogrens skin sle systemic types vasculitides
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
Cryoglobulins are ... with cryoglobulin ... Hyperviscosity syndrome ... • Arthralgia, arthritis ... #Rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
syndrome in 80% ... arthralgia, and arthritis ... SLE), rheumatoid arthritis ... diagnosis #types #classification ... #rheumatology #
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
drug eruptions, paraneoplastic ... Urticarial/LCV) - Cryoglobulinemic ... Disease • Cogan syndrome ... #skin #dermatology ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ANCA +MPO) • Cryoglobulinemic ... Low levels mixed cryoglobulinemia ... Serologies for Cryoglobulins ... differential #diagnosis #rheumatology ... #classification
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... , sepsis or cryoglobulinemia ... to medium-sized arteries ... Calciphylaxis • Cryoglobulinemia ... Antiphospholipid syndrome
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... purpura • Mixed cryoglobulinemia ... • Goodpasture syndrome ... • Giant cell arteritis ... rash #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... ANCA-associated vasculitis ... Non-autoimmune rheumatologic ... • Mesenteric vasculitis ... Erythematosus #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
) • Cutaneous vasculitis ... : • 7%, Cryoglobulinemia ... Arthralgia and Arthritis ... Adenocarcinoma Treatment ... #Rheumatology #
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