8 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... • Secondary ... #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... 1,500 cells/µL Workup ... • Screen for secondary ... Differential #diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... Secondary Causes ... Hypereosinophilia #Syndrome ... #HES #eosinophilia ... #diagnosis #hematology
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
Causes of Secondary ... • Cushing’s syndrome ... Acromegaly #Secondary ... Causes #Screening #Workup ... #table
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... Hypertension - Workup ... with previously stable ... Jcortesizaguirr #Secondary ... #Hypertension #Workup
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... formed or don’t work ... DDX: Rule Out Secondary ... Workup: • Complete ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... develop leukostasis syndrome ... • Tumor lysis syndrome ... bone marrow and secondary ... #Leukemia #Hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
pass = Dangerous secondary ... Chronic & Rx-related Secondary ... ESRD & CAD • Eosinophilic ... cell activation syndrome ... Differential #Diagnosis #hematology