15 results
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
engulf foreign pathogens ... System: opsonize pathogen ... #Inflammation #pathophysiology ... #immunology
Innate Immune Cells - Pathophysiology
The innate immune system consists of granulocytes, mast cells, natural killer cells,
Immune Cells - Pathophysiology ... require previous pathogen ... internalizing pathogens ... Immune #Cells #Pathophysiology ... #immunology
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
associated with CD4 ... or CD8, depending ... intracellular pathogen ... ImmuneResponses #immunology ... #pathophysiology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
IL-2 Muromonab-CD3 ... #Pharmacology #Pathophysiology ... #immunology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
produced from pathogens ... present Ag to CD4 ... Opsonization: Abs coat pathogens ... Humoral #Immunity #pathophysiology ... #immunology
How dendritic cells (DCs) orchestrate adaptive immunity
1- Sensing of microbial and damage signals by DCs
2- Phenotypic
activation 3- DC ... adaptive #immunity #immunology ... #pathophysiology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
dendritic cell (DC ... activate naive CD4 ... #asthma #pathophysiology ... #inflammatory #immunology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
-> Particular CD4 ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... comorbidities: • CBC ... respiratory viral pathogen ... #COPD #AECOPD #Algorithm
Diagnostic approach to the admitted patient with possible COVID-19

Initial evaluation
- Chest X-ray
- Lung ultrasound (thorough "lawn-mower"
and other viral pathogens ... - CBC with differential ... iBookCC #COVID19 #algorithm