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diagnosis treatment ibd gastroenterology differential hemophagocytic hlh humoral immunology inflammatory iris lymphohistiocytosis pulmonary reconstitution syndrome abscess aecopd aids asymptomatic causes
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
of the adaptive immune ... associated with CD4 ... or CD8, depending ... intracellular pathogen ... ImmuneResponses #immunology #pathophysiology
Perianal Crohn's Disease - IBD Algorithm • 5-40% w perianal fistula • ↑ risk if colonic
Disease - IBD Algorithm ... risk if colonic CD ... Crohns #Disease #IBDAlgorithm ... #IBD #Algorithm ... gastroenterology #management
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
produced from pathogens ... present Ag to CD4 ... Opsonization: Abs coat pathogens ... amplitude of secondary immune ... Humoral #Immunity #pathophysiology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD) Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... comorbidities: • CBC ... respiratory viral pathogen ... #COPD #AECOPD #Algorithm ... #Management #Exacerbation
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology Risk factors: - Low CD4 count - Disseminated OI -
Immune Reconstitution ... Syndrome (IRIS) - Pathophysiology ... factors: - Low CD4 ... Restoration of exuberant pathogen-specific ... Syndrome #IRIS #Pathophysiology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Immune Reconstitution ... depend on the pathogen ... involved Pathogens ... edema Other Pathogens ... Differential #Diagnosis #Management
Functional GI Disorders in IBD - IBD Algorithm Background: • 25-40% of IBD in remission have IBS
narcotic use FGID Pathphysiology ... Altered motility • Immune ... Disorders #IBS #IBDAlgorithm ... #IBD #Algorithm ... gastroenterology #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... that disrupts immune ... Others: Cellular immune ... Lymphohistiocytosis #diagnosis #management
Asymptomatic Ileitis - IBD Algorithm • Found on 0.1-21% of non-diagnostic colonoscopies • Low likelihood of
Ileitis - IBD Algorithm ... of representing CD ... Asymptomatic #Ileitis #IBDAlgorithm ... #IBD #Algorithm ... gastroenterology #management
Emphysematous Cystitis Epidemiology: • Usually middle-aged diabetic women • Other RF: neurogenic bladder, urinary tract outlet obstruction,
urinary catheter and immune ... Pathophysiology: ... also important Management ... pyelonephritis CMC ... Cystitis #diagnosis #management
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