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diagnosis treatment ibd differential gastroenterology aids hemophagocytic hlh humoral immunology inflammatory lymphohistiocytosis pulmonary reconstitution syndrome abscess aecopd asymptomatic causes cellular
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology Risk factors: - Low CD4 count - Disseminated OI -
Inflammatory Syndrome (IRIS ... ) - Pathophysiology ... factors: - Low CD4 ... Restoration of exuberant pathogen-specific ... #Pathophysiology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Immune Reconstitution ... depend on the pathogen ... involved Pathogens ... edema Other Pathogens ... Differential #Diagnosis #Management
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
of the adaptive immune ... associated with CD4 ... or CD8, depending ... intracellular pathogen ... ImmuneResponses #immunology #pathophysiology
Perianal Crohn's Disease - IBD Algorithm • 5-40% w perianal fistula • ↑ risk if colonic
Disease - IBD Algorithm ... risk if colonic CD ... Crohns #Disease #IBDAlgorithm ... #IBD #Algorithm ... gastroenterology #management
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
produced from pathogens ... present Ag to CD4 ... Opsonization: Abs coat pathogens ... amplitude of secondary immune ... Humoral #Immunity #pathophysiology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD) Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... comorbidities: • CBC ... respiratory viral pathogen ... #COPD #AECOPD #Algorithm ... #Management #Exacerbation
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
reactivation of latent pathogens ... • IRIS might ... occur when the CD4 ... required until immune ... patients with IRIS
Functional GI Disorders in IBD - IBD Algorithm Background: • 25-40% of IBD in remission have IBS
narcotic use FGID Pathphysiology ... Altered motility • Immune ... Disorders #IBS #IBDAlgorithm ... #IBD #Algorithm ... gastroenterology #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... that disrupts immune ... Others: Cellular immune ... Lymphohistiocytosis #diagnosis #management
Asymptomatic Ileitis - IBD Algorithm • Found on 0.1-21% of non-diagnostic colonoscopies • Low likelihood of
Ileitis - IBD Algorithm ... of representing CD ... Asymptomatic #Ileitis #IBDAlgorithm ... #IBD #Algorithm ... gastroenterology #management
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