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diagnosis rheumatology vasculitis oncology allergy classification cll compared dermatologic dermpath erythemas gpa granulomatosis immunology lesions lupus lymphocytic management pathergy polyangiitis
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
EGPA • Solid cancers ... Vasculitis #dermpath #dermatology ... #semiology #signs ... #manifestations ... #differential
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... • Goodpasture syndrome ... disease • Non-Hodgkin ... Polyangiitis #GPA #dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Cancer affecting ... weeks without infection ... Physical Exam/Signs ... Hepatomegaly • Skin ... workup #oncology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... with Lupus: • Chronic ... cyclophosphamide) • Hodgkin ... lymphoma and leukemia
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Manifestations: ... vasculitis) • Cutaneous ... syndrome (Clinical ... disease) Differential ... #management #signs
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... : CNS manifestations ... CLL -> Invade Skin ... #Hematology #Oncology
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
(cutaneous or systemic ... presenting with erythematous ... associated with cancers ... #table #differential ... #diagnosis #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... : erythematous nodules ... VASCULITIS: • Behçet ... to exclude are infections ... purpura: strong sign
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
Skin trauma → Erythematous ... following: • Behcet ... • Chronic myeloid ... leukemia (CML) ... allergy #immunology #dermatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... : Erythematous nodules ... Eosinophilia, asthma, chronic ... vasculitis • Behcet
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