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diagnosis rheumatology oncology allergy classification compared dermatologic erythemas gpa granulomatosis immunology lupus lymphocytic management pathergy polyangiitis rash signs sle sweet
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... : CNS manifestations ... -> Invade Skin: ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Cancer affecting ... weeks without infection ... Hepatomegaly • Skin ... #CLL #Chronic ... workup #oncology #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... • Goodpasture syndrome ... disease • Non-Hodgkin ... Polyangiitis #GPA #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... with Lupus: • Chronic ... cyclophosphamide) • Hodgkin ... lymphoma and leukemia
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... Manifestations: ... ) • Cutaneous Lesions ... syndrome (Clinical ... disease) Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... : erythematous nodules ... : • Behçet Syndrome ... lupus erythematosus ... to exclude are infections
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Most common extra cutaneous ... general feeling of ill ... Leukocytoclastic vasculitis ... #diagnosis #dermatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... : Erythematous nodules ... Eosinophilia, asthma, chronic ... • Behcet syndrome ... #Rheumatology
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
(cutaneous or systemic ... of necrotizing vasculitis ... associated with cancers ... #table #differential ... #diagnosis #dermatology
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
Skin trauma → Erythematous ... following: • Behcet ... • Chronic myeloid ... leukemia (CML) ... allergy #immunology #dermatology
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