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diagnosis rheumatology hematology classification cryoglobulins dermatologic dermpath gpa granulomatosis lesions oncology paraproteinemias polyangiitis rash semiology signs types
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... EGPA • Solid cancers ... #manifestations ... #pathology #lesions ... #differential
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Syndrome: • Clinical ... • Autoimmune diseases ... Henoch-Schönlein purpura) • Cutaneous
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... Associated Disorders ... Clinical Manifestations ... Biopsy: Typical pathologic ... Antiphospholipid syndrome
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... Manifestations: ... gangrenosum • Cutaneous ... hypertrichosis, hyperpigmentation ... #Monoclonal #Differential
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... Rarely dominate the clinical ... reticularis Differential ... • Goodpasture syndrome
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