8 results
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
of Cutaneous Vasculitis ... Identification of causes ... #dermatology #semiology ... #manifestations ... #differential
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
malignancies, vasculitis ... Clinical Manifestations ... Antiphospholipid syndrome ... #diagnosis #rheumatology ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... - Hemolytic anemia ... #Diagnosis #hematology ... #nonpalpable #dermatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
gangrenosum • Cutaneous ... hypertrichosis, hyperpigmentation ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... Rarely dominate the clinical ... #Dermatologic ... Polyangiitis #GPA #dermatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... presentation) • Cutaneous ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... permanent alopecia Differential ... Clinical Features ... lymphopenia, low PLT • Anemia
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Causes of Monoclonal ... gammopathy, and skin ... changes (POEMS syndrome ... gastric tumors • Hematology ... #diagnosis #hematology