8 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Disease ... anemiaCold ... Diagnosis Monoclonal ... #agglutinin #disease ... #hematology #diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
ulcers - Glomerulonephritis ... Syndrome: • Clinical ... • Autoimmune diseases ... Henoch-Schönlein purpura) • Cutaneous ... #classification
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... EGPA • Solid cancers ... Vasculitis #dermpath #dermatology ... #diagnosis #clinical ... #lesions #differential
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Malignancy • Infections ... sensitivity • Painful ulcers ... • Negative causes ... Biopsy: Typical pathologic ... hematology
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... as non healing ulcer ... Diseases Fellowship ... Mucormycosis #Eschar #dermatology ... #skin #clinical
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... to exclude are infections ... Serologies for Cryoglobulins ... #diagnosis #rheumatology ... #classification
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Nodular or cavitary lesions ... , alcohol, cancer ... Bone Marrow - Anemia ... #differential #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Disease Classification ... papulosquamous lesions ... permanent alopecia Differential ... fibromyalgia) • Infections ... lymphopenia, low PLT • Anemia