10 results
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Clinical Manifestations ... • Negative causes ... Biopsy: Typical pathologic ... #diagnosis #rheumatology ... #hematology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Vasculitis #dermpath #dermatology ... #semiology #signs ... #clinical #manifestations ... #differential
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... ulcers - Glomerulonephritis ... Syndrome: • Clinical ... • Autoimmune diseases ... Henoch-Schönlein purpura) • Cutaneous
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Manifestations: ... vasculitis) • Cutaneous ... ) Differential Diagnosis ... : monoclonal TNF-aIpha ... #management #signs
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
DERMATOMYOSITIS Cutaneous ... manifestations: ... auricular papules Clinical ... severity of the disease ... #dermatology #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... , cutaneous, ocular ... purpura: strong sign ... Serologies for Cryoglobulins ... #diagnosis #rheumatology
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... as non healing ulcer ... University Infectious Diseases ... Mucormycosis #Eschar #dermatology ... #skin #clinical
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
Viral zoonotic disease ... that is caused ... three weeks Clinical ... soles • Oral ulcers ... #Management #Dermatology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... , alcohol, cancer ... Hematologic malignancy ... : Clinical Manifestations ... NTM #Infections #differential
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... auricular papules Clinical ... Muscle atrophy may cause ... had more severe disease ... #dermatology