6 results
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Skin Ulcers by Etiology ... Mycosis fungoides (cutaneous ... • Sickle Cell Anemia ... #ulcerative #skinrash ... #dermatology #Differential
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... ulcers - Glomerulonephritis ... Syndrome: • Clinical ... Henoch-Schönlein purpura) • Cutaneous ... classification #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
sensitivity • Painful ulcers ... • Negative causes ... Biopsy: Typical pathologic ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Viral Infection Clinical ... presentation) • Cutaneous ... younger pts) Differential ... #hematology #diagnosis
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
as non healing ulcer ... trauma, aplastic anemia ... steroid use Dx: skin ... Mucormycosis #Eschar #dermatology ... #skin #clinical
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Causes of Monoclonal ... gammopathy, and skin ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... #diagnosis #hematology