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management antimda5 antimda5dm antinxp2 antinxp2dm causes chronic cll coagulation dic disseminated intravascular leukemia lymphocytic oncology workup
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Cutaneous manifestations ... chest (in a V-sign ... auricular papules Clinical ... #rheumatology # ... dermatology #diagnosis
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... auricular papules Clinical ... positive patients Treatment ... #rheumatology # ... dermatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... involvement (2%) Cutaneous ... • Peripheral smear ... #Coagulation #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... Hepatomegaly • Skin ... • Peripheral smear ... workup #oncology #hematology
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