Pathology clinical dermatology sign pathophysiology hematology skin photo smear diagnosis cutaneous benign rheumatology leukemia dermatofibroma dic chronic

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Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear

Chronic leukemia ... Fibrinolysis & DIC ... CLL -> Invade Skin ... #Hematology #Oncology ... #Diagnosis

Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
• Bleeding
• Recent history

promyelocytic leukemia ... organ damage Clinical ... • Peripheral smear ... #Coagulation #diagnosis ... treatment #management #hematology

Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
• Lymphocytes accumulate in large numbers

Orange or Hep C Clinical ... Physical Exam/Signs ... Hepatomegaly • Skin ... • Peripheral smear ... #oncology #hematology

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