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oncology agglutinin bandemia cbc chronic cll coagulation cold dic disease disseminated hemolytic lymphocytic management mds myelodysplasia myelodysplastic neutrophil syndromes treatment
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... violaceous, nontender cutaneous ... CLL -> Invade Skin ... #Hematology #Oncology ... #Diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... organ damage Clinical ... • Peripheral smear ... #Coagulation #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... • Peripheral smear ... • Neutropenia, anemia ... #oncology #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... presentation) • Cutaneous ... IgM) • Blood smear ... younger pts) Differential ... #hematology #diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... Tissue damage • Leukemia ... #differential # ... #WBC #CBC #hematology ... #pathophysiology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Peripheral Smear ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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