8 results
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
with extensive rouleaux ... PlasmaCell #leukemia #rouleaux ... #formation #Clinical ... #Smear #Hematology ... #Pathology
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Rouleaux formation ... evemariecrane #Rouleaux ... gammopathy #MGUS #Clinical ... #Pathology #Hematology ... #Smear
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
distinguished from “Rouleaux ... occurs when the plasma ... #Clinical #Pathology ... #Blood #Smear # ... #Formation #Hematology
Pity this Giant Pronormoblast from an elderly pt w pure red cell aplasia. In the proper
pure red cell aplasia ... Pure #RedCell #Aplasia ... #Parvovirus #Pathology ... #Smear #Microscopy ... #Hematology #Clinical
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... Biopsy: Typical pathologic ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... Hepatomegaly • Skin ... • Peripheral smear ... workup #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
PT/PTT • Low plasma ... protein C and S Pathophysiology ... organ damage Clinical ... • Peripheral smear ... treatment #management #hematology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... auricular papules Clinical ... diagnosis #management #rheumatology ... #dermatology