11 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Disease: Primary Biliary ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
WBC <2k: Noninflammatory ... lower limbs) • WBC ... presentation with lower WBC ... #Joint #Pain #MSK ... #rheumatology #
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... relative with PBC ... Pathophysiology ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... Pathophysiology ... No extrahepatic biliary ... malignancy #Primary #Biliary ... diagnosis #workup #hepatology
hematopoiesis - leukocyte maturation tree

- Amy Chung, MD, MSc @AmyChung 

#hematopoiesis #leukocytes #maturation #tree #pathophysiology #Hematology
Amy Chung, MD, MSc ... maturation #tree #pathophysiology ... #Hematology #Progenitor ... #Cells #WBC #pathology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
findings Skeletal Pathology ... Degeneration of the hip joints ... • Sacroiliac Joint ... Trendelenburg #Gait #pathophysiology ... signs #diagnosis #msk
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Approach to Joint ... pain from: • Joint ... categories of joint ... Enthesitis: • Site of pathology ... #Pain #MSK #rheumatology
Knee Effusions - Arthrocentesis Interpretation

Inflammatory arthritis:
 • Color: Yellow-> Green
 • Clarity: Opaque
 • Viscosity: Low
Viscosity: Low • WBC ... : Variable • WBC ... analysis: • MSU ... membrane histo-anthology ... diagnosis #septic #joint
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
pericarditis • Hepatic: PBC ... (primary biliary ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Approach to Joint ... , erythema and WBC ... • How many joints ... Differential #Diagnosis #MSK ... #rheumatology #