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diagnosis rheumatology arthritis approach oncology apml cancer clinical differentiation emergencies erythematosus extremity focal fope knee leg lesion lower lupus management
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... Fever/Chills/Joint ... pain/Night sweats ... #causes #differential ... #physicalexam
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Pain History ... Enthesitis: • Site of pathology ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Leg Pain - Differential ... Causes of Leg Pain ... Wounds/ulcers, Edema ... lower #extremity #msk ... #physicalexam
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... , erythema and WBC ... weeks) Can Be Caused ... #pain #Differential ... #Diagnosis #MSK
Focal Periphyseal Edema (FOPE lesion) - MSK Radiology Imaging Findings: • Arrows identifying the characteristic edema-like signal
FOPE lesion) - MSK ... adolescent knee pain ... - Pathologic ... Some studies point ... (save $$) Differential
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Emergencies - Differential ... Diagnosis Framework HEMATOLOGIC ... Leukostasis: • WBC ... Syndrome: • Facial edema ... Malignant Pericardial Effusion
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... myalgias, HoTN, edema ... and effusions, ... initiation • Differential ... diagnosis #management #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Lungs: • Pleural effusions ... Arthritis: • Joint ... pain • Swan neck ... lower extremity edema
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