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diagnosis arthritis differential joint pain rheumatology biliary cholangitis cirrhosis hepatology monoarthritis monoarticular oligoarthritis oligoarticular pagetsdisease pbc polyarthritis polyarticular primary signs
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... intralobular bile ducts causes ... Signs and Symptoms ... cholangitis #diagnosis #workup ... #hepatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Approach to Joint ... or nerve root Symptoms ... Enthesitis: • Site of pathology ... #Joint #Pain #MSK ... approach #workup
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint ... Like in this case ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... to breakage -> Pathologic ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Approach to Joint ... , erythema and WBC ... constitutional symptoms ... weeks) Can Be Caused ... Differential #Diagnosis #MSK
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