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oncology hemolytic leukemia lymphocytic sle classification cold comparison cvid druginduced extravascular gap globulin hemeonc hemolysis hodgkins hypogammaglobulinemia immunodeficiency immunology intravascular
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... for workup, including ... #Diagnosis #Algorithm ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... , CLL, lymphoma, ... . primary cold agglutin ... #differential # ... diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Syndrome (CAS): ... Viral Infection Clinical ... symptoms - most common ... younger pts) Differential ... #anemia #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... Orange or Hep C Clinical ... • Neutropenia, anemia ... #workup #oncology ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... common • Antihistone ... : • Chronic B-cell ... #Diagnosis #Rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... lymphoma (Richter ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
lupus cases, drug-dependent ... Erythematosus ( ... disease Dr. ... comparison #table #rheumatology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Most common cytopenia ... Marrow Failure • Chronic ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Clinical Presentation ... (NSHL) - (most common ... Workup: • Full ... #hematology #oncology ... #management
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