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lymphocytic myelodysplastic aplastic classification common cvid erythematosus gap hemeonc hodgkins hypogammaglobulinemia immunodeficiency immunology lupus lymphoma myelodysplasia protein proteingap sle syndromes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Neutropenia, anemia ... #CLL #Chronic ... #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
(MD) - Diagnosis ... cytopenias (usually anemia ... transformation to acute leukemia ... #MDS #Diagnosis ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... immunophenotype Clinical ... #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... virus (EBV) • Leukemia ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Cell Leukemia ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... gastric tumors • Hematology ... anemia • Other ... #diagnosis #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia ... #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Workup ... number of sites of disease ... classification #hematology ... #oncology #management
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