13 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... disease, liver ... #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
of Alcoholic Hepatitis ... • Serum total bilirubin ... liver disease ( ... #diagnosis #Alcoholic ... #hepatology #criteria
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... liver disease, ... #Algorithm #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... - Serum total bilirubin ... within 7 days) or metabolic ... liver disease ( ... #Diagnosis #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... • Metabolic/Hereditary ... ALT Ratios: • Alcoholic ... liver disease: ... #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
free fatty acid metabolism ... : Viral Hepatitis ... Monitor and Treat Complications ... #Pregnancy #hepatology ... #management #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... slightly elevated • Bilirubin ... or higher • Liver ... : • Viral hepatitis ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
of cholestatic disease ... ALT Ratios: • Alcoholic ... liver disease: ... #chemistry #diagnosis ... #differential #Hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... to acute liver ... - Symptoms of chronic ... regarding need for treatment ... #Management #Hepatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
noninfectious complications ... • Liver diseases ... and hepatitis ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management