10 results
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Serum Ascites Albumin ... - Alcoholic hepatitis ... - Massive liver ... failure - Hepatic ... Diagnosis #hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... cirrhosis or chronic hepatitis ... Fitz-Hugh-Curtis syndrome ... Diagnosis #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... of portal HTN: ascites ... INR, bilirubin, albumin ... Cirrhosis/acute hepatitis ... Diagnosis #causes #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Budd-Chiari syndrome ... Liver disease ... - Alcoholic hepatitis ... Causes #diagnosis #differential ... #hepatology #SAAG
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Mild jaundice, Elevated ... necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
develops (DIC, ascites ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... #Pregnancy #hepatology ... #obstetrics #obgyn
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... Production: • Albumin ... replaced by non-hepatic ... • Gilbert's syndrome ... #Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Injury: • Hepatic ... vein: Budd-chiari syndrome ... specificity to elevated ... diagnosis #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... malignancies, Hepatic ... diagnosis #workup #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Total Protein - Albumin ... concentration minus albumin ... changes (POEMS syndrome ... Sarcoidosis) • Liver ... Gap #ProteinGap #differential