7 results
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
and extrinsic pathways ... Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... #differential #hematology ... #coagulation
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... #Coagulation #Cascade ... diagnosis #models #hematology ... Rivaroxaban #Edoxaban #heparin ... #pathway
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
unfractionated heparin ... deficiencies: Contact pathway ... to the common pathways ... #differential #hematology ... #coagulation
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... dysfunction (25%) • Hepatic ... 100mg/dL) - Heparin ... causes #treatment #management ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor of a coagulation ... the intrinsic pathway ... Acquired: • Heparin ... intravascular coagulation ... Differential #Diagnosis #Hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... Diagnosis: • Clinical ... Management: • ... A/C if clinical ... #Treatment #Hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
diagnosis and initial management ... based primarily on clinical ... #Diagnosis #Management ... #Hematology #HIT ... #Heparin #Induced