8 results
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
the PT and the aPTT ... and extrinsic pathways ... in the common pathway ... to the common pathway ... differential #hematology #coagulation
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... deficiencies: Contact pathway ... Pre-analytical cause ... to the common pathways ... #Prolonged #Causes
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... thrombin (extrinsic pathway ... FXIIa (intrinsic pathway ... models #hematology #pathophysiology ... Edoxaban #heparin #pathway
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
the intrinsic pathway ... the extrinsic pathway ... in the common pathway ... and extrinsic pathways ... discern these causes
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
Review of the Coagulation ... and intrinsic pathways ... Initiation phase caused ... models (i.e. common pathway ... models #hematology #pathophysiology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... pathways. ... infections are common causes ... #glomerular #testing
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... pathways. 6) SPEP ... infections are common causes ... diagnosis #initial #testing
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... Rapoport-Leubering pathway ... Phosphate is a cause ... renal phosphorus wasting ... respiratory #hypoxia #pathophysiology