31 results
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
and extrinsic pathways ... in the common pathway ... Causes include : ... to the common pathway ... #differential #hematology
Evaluation Algorithm of Patients with Bleeding

#Differential #Bleeding #Superficial #Deep #Causes #Algorithm #Hematology
Evaluation Algorithm ... Patients with Bleeding ... #Differential #Bleeding ... Superficial #Deep #Causes ... #Algorithm #Hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
BEARING CHILD PATHWAY ... FLAGS - In all cases ... cell disease Rheumatology ... #Limping #NWB #Algorithm ... #Pathway #Child
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
the intrinsic pathway ... the extrinsic pathway ... in the common pathway ... and extrinsic pathways ... discern these causes
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... Normal PT (INR) - Bleeding ... PT (INR) - No Bleeding ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
DOACs thereby leading ... P-glycoprotein pathway ... with the CYP3A4 pathway ... P-glycoprotein pathway ... Chemotherapy #Oncology #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... inflammation, leading ... • Inflammatory Pathway ... cyclophosphamide • Ischemic Pathway ... CNS #neurology #rheumatology
Arrhythmias - Differential Diagnosis Algorithm
May present as: palpitations, dizziness, syncope, chest discomfort
Cardiac Causes:
 - Structural
Differential Diagnosis Algorithm ... • Accessory pathway ... ) Non-Cardiac Causes ... Differential #Diagnosis #Algorithm ... #causes
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... deficiencies: Contact pathway ... Pre-analytical cause ... to the common pathways ... #differential #hematology
Pharmacologic treatment algorithms by Global Initiative for Chronic Obstructive Lung Disease grade. Highlighted boxes and arrows
Pharmacologic treatment algorithms ... preferred treatment pathways ... Management #Pulmonary #COPD