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diagnosis differential abnormal coagulation pt management pathophysiology prolonged anticoagulant anticoagulation apixaban bleeding bruising cascade child clot dabigatran edoxaban enzymes essential
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
the PT and the aPTT ... and extrinsic pathways ... in the common pathway ... to the common pathway ... #differential #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... deficiencies: Contact pathway ... Pre-analytical cause ... to the common pathways ... #differential #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
BEARING CHILD PATHWAY ... FLAGS - In all cases ... - Sickle cell disease ... #Limping #NWB #Algorithm ... #Pathway #Child
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin (extrinsic pathway ... FXIIa (intrinsic pathway ... and endothelial cells ... diagnosis #models #hematology ... Edoxaban #heparin #pathway
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
the intrinsic pathway ... the extrinsic pathway ... in the common pathway ... and extrinsic pathways ... discern these causes
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... determine choice of pathway ... for users of the pathway ... Abnormal USS may well ... #Hepatology #Liver
Hypophosphatemia and Hypoxia - Pathophysiology ↓ Phosphate leads to ↓ red cell 2,3-DPG and a reduction
leads to ↓ red cell ... Rapoport-Leubering pathway ... leads to a ↓ red cell ... Phosphate is a cause ... patients with COPD
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... meet criteria for hematologic ... or evolve into hematologic ... Clinical Clues: ... - Complement pathway
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
Langerhans Cell ... driven by MAPK pathway ... Incidence: 4–5 cases ... Birbeck granules (EM ... therapies for cases
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... JAK-STAT signaling pathway ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
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