16 results
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and extrinsic pathways ... in the common pathway ... to the common pathway ... #differential #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
the intrinsic pathway ... the extrinsic pathway ... in the common pathway ... and extrinsic pathways ... Differential #Diagnosis #Hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
• Prolonged PT ... (INR) - Bleeding ... (INR) - No Bleeding ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Coagulation Cascade Mnemonic - PITT vs PET
PITT (with an I) = Intrinsic = APTT
E)= Extrinsic=PT ... , 7, 10 Common Pathway ... PET #diagnosis #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... deficiencies: Contact pathway ... to the common pathways ... #differential #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin (extrinsic pathway ... FXIIa (intrinsic pathway ... thrombin #clot #PT ... diagnosis #models #hematology ... Edoxaban #heparin #pathway
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
BEARING CHILD PATHWAY ... neurology, back pain Haematology ... cell disease Rheumatology ... #Limping #NWB #Algorithm ... #Pathway #Child
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
DOACs thereby leading ... P-glycoprotein pathway ... with the CYP3A4 pathway ... P-glycoprotein pathway ... Chemotherapy #Oncology #Hematology
Pharmacologic treatment algorithms by Global Initiative for Chronic Obstructive Lung Disease grade. Highlighted boxes and arrows
Pharmacologic treatment algorithms ... preferred treatment pathways ... Management #Pulmonary #COPD
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
inflammation, leading ... • Inflammatory Pathway ... cyclophosphamide • Ischemic Pathway ... CNS #neurology #rheumatology