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humoral rheumatology asplenia calcium comparison deposition diagram differential disease glomerulonephritis gout immunocompromised immunology infections management membranoproliferative mpgn nephrology pseudogout pyrophosphate
Infectious Risks in Asplenia and Deficiencies in Humoral Immunity and Complement - Venn Diagram Humoral Immunity: •
and Complement ... by antibodies) pathway ... Mannose-binding Lectin pathway ... • Alternative pathway ... #differential #diagnosis
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
staining (lg + complement ... MGPN • Complement ... pathway • C3 ... immune deposits on EM ... MPGN #nephrology #diagnosis
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Humoral Immunity ... contribute to immunity ... the classical pathway ... exposure #Humoral #Immunity ... #pathophysiology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... activate inflammatory pathways ... culture used to diagnose ... stain and culture- Diagnose ... #rheumatology #Diagnosis
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
) Pathophysiology ... calcium to form CPP ... activate inflammatory pathways ... culture used to diagnose ... #Rheumatology #diagnosis
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