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diagnosis glomerular glomerulonephritis nephrotic workup c5c9deficiency child differential disease enzymes hepatology immunology initial lfts limping liver membranoproliferative mpgn nephritic nephritis
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
staining (lg + complement ... MGPN • Complement ... pathway • C3 ... immune deposits on EM ... Glomerulonephritis #MPGN #nephrology
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
fatality is rare Normal ... : The complement ... pathway is a non-specific ... alternative, or lectin pathway ... #pathophysiology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
BEARING CHILD PATHWAY ... splenomegaly, abnormal ... neurology, back ... #Limping #NWB #Algorithm ... #Pathway #Child
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... determine choice of pathway ... decision for repeat testing ... for users of the pathway ... #Algorithm #Hepatology
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... pathways. ... #glomerular #testing ... nephrotic #nephritic #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... pathways. 6) SPEP ... diagnosis #initial #testing ... #nephrology #nephrotic
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