7 results
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
the Coagulation Cascade ... and intrinsic pathways ... (i.e. common pathway ... #Coagulation #Cascade ... #hematology #pathophysiology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin (extrinsic pathway ... FXIIa (intrinsic pathway ... PTT #diagnosis #models ... #hematology #pathophysiology ... Edoxaban #heparin #pathway
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
response: The complement ... pathway is a non-specific ... alternative, or lectin pathway ... cascade -> MAC ... #pathophysiology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
integrity Clotting cascade ... the intrinsic pathway ... the extrinsic pathway ... in the common pathway ... and extrinsic pathways
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
activation • Complement ... the classical pathway ... (see Complement ... sites (e.g. lymph nodes ... Humoral #Immunity #pathophysiology
Pathogenesis of Select Causes of Constipation in Adults and in Elderly

 • Mechanical (ex. Bowel Obstruction,
colonic mucosa, leading ... anal canal -> Evacuation ... unknown, many pathways ... excitatory neural pathways ... #constipation #pathophysiology
Bulimia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: Some
causing disordered feeding ... Factors • Reward Pathway ... response of reward pathways ... Appearance over-evaluation ... BulimiaNervosa #pathophysiology