7 results
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
and extrinsic pathways ... in the common pathway ... to the common pathway ... amyloidosis #Abnormal ... #differential #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... deficiencies: Contact pathway ... to the common pathways ... Jcortesizaguirr #Abnormal ... #differential #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/ABNORMAL PTT ... the intrinsic pathway ... the extrinsic pathway ... in the common pathway ... and extrinsic pathways
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
BEARING CHILD PATHWAY ... FLAGS - In all cases ... splenomegaly, abnormal ... #Limping #NWB #Algorithm ... #Pathway #Child
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Idiopathic • Normal ... differential #diagnosis #algorithm ... #rheumatology
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... meet criteria for hematologic ... kidney function • Abnormal ... tubulopathy) - Complement ... pathway activation
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... JAK-STAT signaling pathway ... are usually near-normal ... • Treatment algorithms ... Thrombocythemia #ET #hematology