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diagnosis differential essential et gammopathy glomerulonephritis limping management mgrs monoclonal nwb pediatrics peds progressive rapidly renal rheumatology rpgn significance thrombocythemia
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
PATHWAY RED FLAGS ... - In all cases ... splenomegaly, abnormal ... #Limping #NWB #Algorithm ... #Pathway #Child
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Idiopathic • Normal ... differential #diagnosis #algorithm ... #rheumatology
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... meet criteria for hematologic ... kidney function • Abnormal ... tubulopathy) - Complement ... pathway activation
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... JAK-STAT signaling pathway ... are usually near-normal ... • Treatment algorithms ... Thrombocythemia #ET #hematology
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