16 results
Infectious Risks in Asplenia and Deficiencies in Humoral Immunity and Complement - Venn Diagram
Humoral Immunity:
 •
Infectious Risks in ... by antibodies) pathway ... Mannose-binding Lectin pathway ... • Alternative pathway ... immunocompromised #infections #differential
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
-10000x higher in ... deficiency than in ... pathway is a non-specific ... alternative, or lectin pathway ... #pathophysiology
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
pathway in the ... understanding of pathophysiology ... To propose new classifications ... Limitations of the IFN ... #interferon #IFN
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
activation • Complement ... the classical pathway ... (see Complement ... proliferate and differentiate ... Humoral #Immunity #pathophysiology
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
presentations in ... the lab values table ... #Diagnosis #Algorithm ... #Differential # ... Peds #Pediatrics #Table
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
neurotransmitter pathways ... methionine (SAM) pathway ... activity -> Decrease in ... Secondary #Causes #Differential ... #Diagnosis #Pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... mediated (Negative IF ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
patterns seen in ... Metabolism A table ... and Pediatrics In ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... Peds #Pediatrics #Table
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... determine choice of pathway ... for users of the pathway ... LFTs #Abnormal #Algorithm ... Liver #Enzymes #Differential
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
are deposited in ... Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology ... Diagnosis #Reactions #Table