6 results
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... pathways that lead ... hyperglycemia in type ... ominous octet it works
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Complement activation ... #Classification ... #Pathophysiology ... Diagnosis #Reactions #Table
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Through 2 Different Pathways ... Types: • Type ... • Type III Often ... • Low serum C4 complement ... #classification
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
or alternative complement ... pathways. ... cryoglobulinemias (types ... glomerular #testing #workup
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
or alternative complement ... pathways. 6) SPEP ... cryoglobulinemias (types ... glomerular #disease #workup
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Diagnostic Workup ... guide subtype classification ... tubulopathy) - Complement ... pathway activation ... vasculitis Types