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diagnosis differential antibodies classification antineutrophil comparison cryoglobulins diseases druginduced patterns sjogrens syndrome table tafro thrombocytopenia types vasculitides
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... Jcortesizaguirr #ANA ... #Antinuclear #Antibody ... antibodies #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antibody refers ... Positive ANA ≠ Autoimmune ... (SLE), Systemic ... (SLE), Systemic ... #patterns #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... DDX: • ANCA (Antineutrophil ... cytoplasmic antibody ... lupus erythematosus ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... Vasculitis: + MPO-ANCA ... lupus erythematosus ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... Workup: - ANA ... months to years) Systemic ... Workup: - ANA ... #table #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... : ANCA Associated ... often causes arthritis ... + MPO) Cryoglobulinemic ... Differential #Diagnosis #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... 7%, Cryoglobulinemia ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
lupus erythematosus ... (SLE), Sjögren’ ... s syndrome, ANCA-associated ... vasculitis - Infectious ... #rheumatology #
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