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diagnosis cardiology antibody arteritis champs complement dermatology erythematosus gca giantcell glomerulonephritis hemolytic hypocomplementemia infectiousdiseases low mnemonic petechiae petechial physicalexam progressive
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Atypical HUS, autoimmune ... (RA, Sjogren's) ... Lupus Erythematosus ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
• Blood smear: Differential ... 2) LOOK FOR a cause ... → Systematic screening ... #diagnosis #management ... #treatment #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... #differential # ... diagnosis #algorithm ... #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Schonlein Purpura - Endocarditis ... Palpable Rash: - Autoimmune ... Vasculitis (lupus ... , RA, Sjogren's, ... #Causes #dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... #Syndrome #Rheumatology ... #Diagnosis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... dermatomyositis, Sjogren ... • Libman-Sacks endocarditis ... #Diagnosis #Rheumatology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
regurgitation • Autoimmune ... Cerebral > Splenic, pulmonary ... valvular disease • Vasculitis ... Leukocytosis, anemia ... #diagnosis #management
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... very remarkable w/differential ... complaints- anemia ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
regurgitation • Autoimmune ... Cerebral > Splenic, Pulmonary ... valvular disease • Vasculitis ... Leukocytosis, anemia ... hematuria, + RF Treatment
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
mesothelioma, etc - Autoimmune ... lupus erythematosus ... ANCA-associated vasculitis ... Hypoalbuminemia Treatment ... #rheumatology #
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